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Courses

  1. A.     Undergraduate

COURSE CODE:

COURSE TITLE

Units

PCG

201

ORGANISED VEGETABLE DRUGS (3UNITS)

Introductory Pharmacognosy, micromorphology, anatomy of herbs and leaves.  Monographs.The Microscope-Optical principles & techniques macroscopy, microscopy.  The plant cell, cell-wall structure and cell inclusions.Micromorphology of subterranean organs barks and wood.  Monographs. Chemo-microscopy. Micromorphology of fruits, seeds and flowers monographs, chemo-microscopy, micro-metry

 

Field trip

3

PCG

202

UNORGANISED VEGETABLE DRUGS (1UNIT)

Introduction to primary metabolism Photosynthesis, Saccharides, Osazones, Commercial starches .Pharmaceutical Gums, resins, balsams,  mucclages – natural sources and processing, identification and uses

 

1

 

PCG

301

 

SEPARATION TECHNIQUES (2 UNITS)

 

Principles and applications of chromatography. Adsorption and Partition chromatography. Factors affecting resolution.  Paper, TLC, GLC, Quantitative chromatography. HPLC, Centrifugal liq. Chrom.  DCCC, Electrophoresis etc.  Quantitative chromatography.  Application to Pharmacy

 

2

PCG

302

 DRUGS OF BIOLOGICAL ORIGIN (3 UNITS)

 

Medicinal plant constitutents.  Drugs from natural sources.  Concept of secondary metabolism and significance to man as sources of drugs.

Glycosides. Alkaloids, Flavonoids, lipids, tannins, vitamins and enzymes.  Field trip/Recognition of medicinal plants

3

 

PCG

401

BIOGENESIS OF NATURAL PRODUCTS (2 UNITS)

Significance of study, unit transformations, sources of energy and enzymes.  Shikimic acid and pathways leading to aromatic natural products. Origin of isoprene unit and pathways leading to isoprenoids, inter-relationship of various terpenoids.

2

 

PCG

402

MEDICINAL PLANT/TRADITIONAL MEDICINE/POISONOUS PLANTS (3 UNITS)

 

Traditional Medicine.  Definitions, Methods. TM as source of new drugs/new methods of treatment.  Role of TMP/healing methods in Health Care Delivery.  Integration/co-recognition . Science evidence supporting use of medicinal plants in some remedies and practices.

Medicinal plants of local significance Botanical and ethnobotanical/ethnopharmacological considerations.  Recognition, geographical distribution and habitat.  Preparation and use of herbarium specimens in medicinal plant evaluation. Poisononous/Ordeal plants and fungi. Identification, toxic principles, clinical manifestations, treatment and antidote of poisoning Controlled plants.  Marihuana, Coca, opium, mushrooms etc.

 

Field trip:  -

3

 

PCG

501

EVALUATION OF PHYTOPHARMACEUTICALS  AND SURGICAL DRESSINGS (3 UNITS)

Plant authentication, Principles of Systematics.  Chemical races and relevance to Pharmacy, Quantitative Microscopy

 

Evaluation & Standardization of Natural Products/Herbal Medicines.  Quality Assurance Monographs. Surgical Dressings.  Evaluation & relevance to wound healing

3

 

 

PCG

502

 

 RECENT ADVANCES

(1 UNIT)

Natural Products and Pharmaceutical Raw Materials.   Alternative sources of local raw materials.  Contribution of plants and plant products in treatment of diseases: - Sickle cell anaemia, anti-inflammatory agents, anti-cancer agents, anti-hypertensives .Antimalarials, immunomodulators, HIV/AIDS. Herbicides Insecticides, Pesticides molluscicides.

1

 

           

 

  1. B.     Postgraduate

 

Course

Code

Course Description/Synopsis

Units

PCG       701

Biogenesis of Plant Secondary Metabolites

 

Significance of study of biosynthetic pathways methods of investigation. Biological origin of isoprene unit and pathways leading to production of plant terpenoids.  Specific drug examples. The Shilkimic acid pathway and pathways leading to production of aromatic compounds.  Specific drug examples.

3

PCG 702

Medicinal Plants and Raw Materials

Source of drug adjuvants and galenicals.  Factors involved in the production of drug from natural sources.  Cultivation, collection, processing and storage.  Commercial requirements. Propagation, Tissue culture. Genetics, possibility and prospects of medicinal plant production in Nigeria.  Chemical races.  Nigerian medicinals and poisonous plants in traditional medicine. Prospects and problems of sourcing raw materials from local medicinal plants for the pharmaceutical industry.

 

Field trip

3

PCG 703

Application of Microscopic Techniques In Pharmacognosy

Preparation of herbarium specimens.  Use of flora & keys for identification.  Microscopy and Advanced histological techniques.  Quantitative microscopy and Photomicrography. Applications of drugs evaluation with specific examples from official pharmacopoial and Nigerian medicinal plants.

3

PCG 704

Recent Advances in Pharmacognosy

Contributions of plants and plant products in the treatment of diseases, cardiovascular diseases.  Anti-malarias steroids and steroidal hormones.  Anti HIV/AIDS agents of plant origin. Cancer chemotherapy and laxatives, anti-fertility agents, molluscicides, antimicrobial agents.  Aloevera, Ginkgo and Ginseng products. . Allelopathy.

3

PCG 705

Medicinal Plant Taxonomy

Classical plant taxonomy and chemotaxonomy chemotaxonomic groups and markers

 

2

PCG 706

Research Methods In Pharmacognosy

In vitro and in vivo biologically monitored phytochemical separations and relevance to drug discovery from nature.  Selection of plants for bioactivity guided fractionation processes that lead from plants to pharmacologically active pure compounds.  Targets for bioassay.  Benchtop techniques and major areas of research and discoveries. Advanced treatment of research methods in natural product research.  Advanced spectroscopic techniques (UV, IR, NMR, MS etc) in structural elucidation and assessment of natural product purity and potency.

 

Micro-methods  for screening for bioactive compounds. Advanced Microscopic techniques in assessment of natural product purity and potency.

 

4

PCG 707

Advanced Laboratory Course

Practical work designed to illustrate the principle underlying methods discussed in  theory to improve the candidates practical ability and presentation of reports.

3

PCG 708

Seminar and Directed Reading

Designed to acquaint the candidate with current and relevant research topics and developments in Pharmacognosy.

 

3

PCG 709

Drugs from Biological Origin and Phytochemical Analysis

 

The plant and animal kingdom as sources of novel bioactive natural products.  Medicinal plan  phytochemistry. Principles of extraction, detection and isolation of secondary metabolites of medicinal interest.  Fractionation  of plant extracts and purification  methods.  Principles of phytochemical analysis of medicinal plants’ constituents.

3

PCG 710

Project

Candidates will present a report incorporating a review of relevant literature and an account of laboratory work in a selected topic.

 

6

EMS 724

Basic Statistical Procedures

Role of statistics in human biology and medicine.  Revision of basic concepts of probability and descriptive statistics.  Significance tests methods based on the normal distribution.  Analysis of variance, Regression and Correlation, Confidence intervals.  Format and informat tests of assumptions.  Tests for discrete data.  Contingency tables.  Basic distribution free methods.  Mann Whitney, Sign test, spearman and Kendall correlation, Kdruskall, Wallis tests.

3

 

 

IN EMESH

MEB

771

Ethnolbotany I (Medicinal Plants)

Scientific approach to the study of plants of proven medicinal values to humans and animals.  Techniques of identification.  Collection and preservation.  Modern methods of herbal preparations.  Toxic plants.  Collection and documentation of ethnobotany.  Phytochemical and biocontrol screening

 

4

 

 

In Botany Dept.

PCG 712

Standardization  and Quality Assurance of Natural Products

Commercial requirements of vegetable, microbial and animal drugs. Microscopical, physico-chemical and biological methods of evaluation.   Monograph compilation, pharmacopoieal standards and specifications.  Prospects and problems of standardization of herbal remedies. General methods of evaluation of vegetable, microbial and animal drugs.  Basic information and standards with respect to potency, identity, safety, purity etc of natural products, Organolept, evaluation. Determinations and relevance of ash extractive values, moisture content

 

4

*PCG 801

Advanced Laboratory Course II

Experimental designs to illustrate advanced phytochemical research techniques aimed at improving candidatespractical ability inPharmacognosy

 

3

*PCG 802

SEMINAR

Current research topics in phytochemistry and medicinal plant research.